BIELENDA Chrono Age 24h Regenerating Anti-Wrinkle Cream 40+ for Night 50ml

CHRONO AGE 24h – Epigenetic protection of skin condition through the regulation of its biological clock.

A properly functioning biological clock ensures a beautiful skin appearance. However, changes in daily activity due to exposure to artificial light, sunlight, and chemical compounds from polluted environments disrupt the precisely programmed circadian cycle of the skin, causing oxidative stress. This leads to cellular degeneration, worsening skin condition, and premature aging.

CHRONO AGE 24h - an innovative line of multifunctional anti-wrinkle cosmetics that counteract the biological effects of environmental threats.

Experts from the Bielenda Scientific Laboratory, in collaboration with researchers from the Jagiellonian University Collegium Medicum Faculty of Pharmacy, have selected high-potential ingredients to regulate the skin’s natural biological cycle and provide multi-level protection:

• Epidermal level – Biopolymer shield
• Cellular level – Antioxidation and chelation
• DNA level – Epigenetic stimulation

Bielenda's patented biomimetic cosmetic base, along with its active ingredients, creates a microscopic protective mesh on the skin’s surface, preventing harmful smog particles from penetrating and damaging skin cells.

• Regulates biological clock genes: BMAL1, CLOCK, PER1
• Activates the longevity gene SIRT1, which plays a crucial role in skin aging processes
• Stimulates collagen production by activating the expression of genes COL1A1 and COL1A2
• Acts as an antioxidant—prevents reactions leading to skin cell damage
• Binds heavy metals and prevents their penetration into the epidermis
• Prevents photoaging caused by UV radiation

The active ingredients of the CHRONO AGE 24h line modulate gene expression—acting as chemical switches that reactivate beneficial genes "turned off" by external factors while inhibiting genes that negatively impact the skin.

Regenerating Night Anti-Wrinkle Cream for mature and sensitive skin.

The epigenetic repair complex in the cream prevents biological clock gene dysregulation, reducing skin cells' susceptibility to damage. In synchronization with the skin’s natural nighttime regeneration process, it initiates reparative actions at all levels. It rebuilds and strengthens the skin’s natural lipid barrier and stimulates collagen production.

Regular use of the cream ensures intensive nighttime skin revitalization:

• Intensively regenerates, effectively smooths
• Increases skin elasticity

How to use:

Every evening, massage the cream into cleansed skin on the face, neck, and décolleté.

Ingredients:

Aqua (Water), Persea Gratissima (Avocado) Oil, Sorbitan Stearate, Squalane, Caprylic/Capric Triglyceride, Glycerin, Orbignya

Oleifera (Babassu) Seed Oil, Glyceryl Stearate, Cetearyl Alcohol, Tocopheryl Acetate, Euphorbia Cerifera (Candelilla) Cera,

Glycine Soja Sterols, Lecithin, Curcuma Zedoaria Rhizome Extract, Morus Alba (White Mulberry) Leaf Extract, Ginkgo Biloba

Leaf Extract, Beta-Sitosterol, Methylsilanol Mannuronate, Coconut Alkanes, 3-O-Ethyl Ascorbic Acid, Dimethiconol, Glycine Soja

(Soybean) Oil, Squalene, Sorbityl Laurate, Sodium Stearoyl Glutamate, Xanthan Gum, Citric Acid, Disodium EDTA, Ascorbyl

Palmitate, Tocopherol, Lavandula Angustifolia Flower Extract, Oryza Sativa (Rice) Starch, Acacia Senegal Gum, Hydrolyzed